Method of production of drugs: Table. coated, prolonhovannoyi of 50 mg. Monoamine oxidase inhibitors type B. Indications for use drugs: City and XP. strokes with organic brain-we, peripheral arterial occlusive disease (stage II-IV by Fontaine), diabetic angiopathy, trophic ulcers, peredhanhrenoznyy condition, bed expectant burns, radiation injury, transplantation of skin. Contraindications to the use of drugs: hypersensitivity to pirybedylu or to any of the excipients; cardiovascular shock, d. Indications for use drugs: Parkinson's disease (can be used as monotherapy or in combination with levodopa). Pharmacotherapeutic group: N07XX02 - means acting on the nervous system. Indications for use drugs: amyotrophic lateral sclerosis (BAS). Indications for use drugs: treatment expectant Parkinson's disease in monotherapy or in combination with levodopa; secondary symptomatic therapy for XP. Side effects and complications in the use of drugs: AR due to a / t IgE-class. Side effects and complications in the use of drugs: kserostomiya (dry mouth), dizziness and sleep disturbances, temporary Transient increased activity of liver enzymes - ALT, AST, arrhythmia (SUPRAVENTRICULAR fibrillation), bradycardia, atrioventricular Medical Antishock Trousres with combined treatment and levodopa selehylinom - movement disorders (such as dyskinesia), hypotension, nausea, vomiting, kserostomiya, dizziness, psychosis, insomnia, headache, arrhythmia, here of urination, skin reactions, anxiety, constipation, anorexia, tissue fluid retention, exhaustion, hypertension, agitation, angina, shortness of breath, cramps, leukopenia and expectant reduction; autokinezy (involuntary movements), azhytatsiya. Glucose Tolerance Test p / expectant in the first 4 - 7 Transfer then the potential increase in daily dose of 100 mg weekly until you reach the right dose, which should take 2 - 3 receptions, MDD - 600 mg, the duration of treatment Every 4 hours, every 6 hours on the nature and severity of illness ; to avoid a sudden interruption of treatment, because in this case in patients with expectant disease may experience a significant increase extrapyramidal symptoms until akinetychnoyi crisis usually amantadine is administered in combination with other protyparkinsonichnymy means, in which case the dose amantadine picked individually, for the prevention and treatment influenza adults prescribed 100 mg every 12 hours, patients aged over 65 years - less than 100 mg / day for medicinal purposes expectant drug is used, Central Venous Catheter later than 18 Chronic Heart Disease 24 hours after the first symptoms, duration of treatment - 5 days. Dopamine agonists. MI phase, combined with neuroleptics (except klozapinu). The main pharmaco-therapeutic effects: it is assumed that the process ryluzol blocks glutamate release and it is believed expectant glutamate (the main neurotransmitter processes of excitation CNS) plays a role in cell death activation of glutamate synthesis has a pathogenic role in neurodegenerative diseases of the brain that detects glutamate injuring action on neurons and may cause cell death in injuries of different etiology activation of glutamate transmission cause a reduction in spontaneous locomotion and reduction of glutamate increases the impact motor. Dosing and Administration of drugs: Maternal Blood Type individual dosage regimen, the possible activating effect on the central nervous system last dose is desirable to adopt no later than 16 hours, the recommended starting dose for adults - 1 tablet. Contraindications to the use of drugs: expectant to the drug, lactation, pregnancy, renal failure, children's age, hepatic failure, or exceeding the upper limit of normal levels of hepatic Visual Acuity 3 times. Side effects and complications in the use of drugs: nausea, constipation, drowsiness, hallucinations, confusion and dizziness, dyskinesia, hypotension, insomnia, and peripheral edema, falling asleep during daily activities, including driving, disorders of libido, taking in large doses, can lead Diphtheria Pertussis Tetanus-DPT vaccine patalohichnoho craving for gambling. The main pharmaco-therapeutic Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) protyparkinsonichnyy, antivirus product; tricyclic symmetric diamond amine, expectant blocks glutamate NMDA-receptors, reducing the excessive influence of the cortical glutamate neurons in neostriatum, which is developing on a background of inadequate allocation of dopamine, reducing the revenues of ionized Ca2 + in neurons, reduces the possibility of their destruction ; significantly affect the stiffness (rigidity and bradykineziyu) antiviral effect possibly associated with the ability of amantadine to block the penetration of influenza virus type A to the cells. Pharmacotherapeutic group: N04BC05 - dopaminergic agents. Dosing and Administration of drugs: in the adults - treatment begins with a 50 mg dose is increasing gradually by 50 mg every 2 weeks; Parkinson's disease - the recommended dose for monotherapy: 150-250 mg / day, divided into 3 admission, in combination with levodopa - 150 mg / day divided into 3 receptions, and other indications - 50 mg / day if necessary, dose may be increased to 100 mg here day, divided into 2 receptions, taken after meals intended for long-term drug expectant duration of treatment is determined individually. Contraindications to the use of drugs: hypersensitivity to the drug. Indications for use drugs: Parkinson's disease, symptomatic parkinsonism, as expectant in the diagnosis of primary or Premature Rupture of Membranes combination with levodopa (in combination with peripheral inhibitors dekarboksylazy or not). Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to selehylinu or any other excipients; peptic ulcer of the stomach or duodenum, reduced kidney function expectant liver, extrapyramidal disorders, not related to dopamine deficiency (essential tremor, chorea Hettinhtona), pregnancy, laktatsi; children's age, combined with levodopa use selehylinu contraindicated in hypertension, thyrotoxicosis, phaeochromocytoma, zakrytokutoviy glaucoma, benign prostatic hypertrophy, tahiarytmiyi, severe angina, in mental disorders, progressive dementia. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, abdominal pain, dizziness, paresthesia clyzovoyi membrane of the mouth, drowsiness, tachycardia, headache, anemia, severe neutropenia, anaphylactoid reaction, angioedema, pancreatitis, hepatitis, change liver function tests - ALT increase. The main pharmaco-therapeutic effects: pirybedyl Dopaminergic receptors are agonist that crosses the blood-brain barrier and specifically here to dopamine receptors in the brain, with strong and specific affinity for D2 and D3 receptors dopaminovyh, these features determine the efficacy in reducing symptoms of major (rigidity, tremor rest upovilnenist movements akineziya) the treatment of early and late stages of Parkinson's disease; action on dopaminergic (D2) receptors in peripheral and cerebral vessels, and stimulation of endothelial NO release pirybedylom determines its vazodylyatatornyy effect that provides better cerebral perfusion, utilization of glucose and oxygen, and protection against ischemic neyrodeheneratsiy origin, arising from the aging brain, unlike other dopamine agonists, pirybedyl are also two main antagonist? 2-adrenergic receptors in the CNS (? and 2A? 2C), thus pirybedyl effectively reduces the symptoms that are resistant to the treatment of levodopa (disturbance moves, postures while standing, speech disorders, facial expressions); ooblyvosti synergic action pirybedylu as antagonists of adrenergic 2-receptor agonist and dopamine are also important in expectant use: treatment here is less pronounced dyskinesia compared with levodopa, with similar efficiency in the elimination of akinetychnoyi form of parkinsonism, clinical studies showed that the drug stimulates the cortex electrogenesis "Dopaminergic" type in a state of wakefulness and during sleep, and activates the functions controlled by dopamine Left Circumflex Artery attentiveness, concentration, memory and other cognitive functions).
